Ultimately, the balance of activity between these two groups of cells may determine whether a person acts to seek out pleasurable experiences or avoid negative ones, says CSHL Professor Bo Li, who led the study. Their work, reported Decemin the journal Neuron, reveals that different classes of neurons control positive and negative motivation, sending opposing signals along a shared motivation-processing brain circuit. Researchers at Cold Spring Harbor Laboratory (CSHL) have zeroed in on an information-processing hub in the brains of mice to discover how neurons there divide the labor to handle these opposing behavioral motivations. negative motivation and may explain behaviors associated with psychiatric disorders like depression or anxiety.ДЄs our brains take in information about the world and use it to steer our actions, two key principles guide our choices: seek pleasure and avoid pain. The region of the brain called the ventral pallidum balances signals that either excite or inhibit neurons to influence the motivation of an animal to seek pleasure or avoid pain.

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What part of the brain controls balance